This is part of the series of 30 exercises developed during the E3D+VET program. The aim of this Erasmus+ program is the immersion in 3D printing of VET centres (website: ). This exercise is composed by 24 interchangeable “puzzle” pieces and a base, where one can put the DNA Base puzzle pieces. • The base ground is a rectangular piece in which 6 puzzle pieces can be allocated; • Each DNA base piece is suggested to be painted with a different colour for better distinction; There are 4 bases (Adenin, Cytosine, Guanine, and Thymine). Each base has a matching base (A and T match; C and G match) Each base piece features the letter of its Name (A= Adenin, C= Cytosine, G= Guanine, and T = Thymine) For a more difficult level the Bases can all have the same end so it will not be so obvious which base matches with which one.